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Disruptive Science

International Project to Help Detect a Liver Disease Called NASH Gets $35M Boost

International Project to Help Detect a Liver Disease Called NASH Gets $35M Boost

International Project to Help Detect a Liver...

Imagine if the only way to know whether you have diabetes was for a doctor to take a biopsy of your pancreas, rather than being able to check your glucose levels using a simple blood test. ...

Treating Cancer by Using Epigenetics, the ‘Software’ of Our Genes

Treating Cancer by Using Epigenetics, the ‘Software’ of Our Genes

Treating Cancer by Using Epigenetics, the ...

All of our cells possess the same set of DNA. So, why is it that some cells turn into skin cells while other cells turn into lung cells — and still other cells go rogue and turn into cancer cells? ...

Are Genetic Tweaks Made by Gene Therapy Handed Down to Offspring?

Are Genetic Tweaks Made by Gene Therapy Handed Down to Offspring?

Are Genetic Tweaks Made by Gene Therapy Handed...

The possibility of finding a treatment or even a cure for genetic disorders such as muscular dystrophy or hemophilia has taken a giant leap forward in recent years with the advent of gene therapy as a way to modify a defective gene or group of genes. ...

The Search for a ‘Liquid Biopsy’ and Other Advances to Diagnose Cancer

The Search for a ‘Liquid Biopsy’ and Other Advances to Diagnose Cancer

The Search for a ‘Liquid Biopsy’ and Other...

A liquid biopsy — a technology that attempts to diagnose a disease through a blood sample rather than by using a tissue sample collected through a traditional biopsy — is just one technology being explored to make cancer diagnosis faster and less invasive. ...

Metabolism and Immunology: Using Lessons From Metabolic Diseases to Treat Autoimmune Disorders

Metabolism and Immunology: Using Lessons From Metabolic Diseases to Treat Autoimmune Disorders

Metabolism and Immunology: Using Lessons From...

By regulating the metabolism of immune cells, researchers are uncovering novel ways to suppress inflammation and treat autoimmune diseases. ...

A Mountaineer Reaches for the ‘Everest’ of his Cancer Research Career

A Mountaineer Reaches for the ‘Everest’ of his Cancer Research Career

A Mountaineer Reaches for the ‘Everest’ of his...

New insights into the immune system are driving a recent resurgence in investigating vaccines that fight cancer tumors.  ...

Inside the Science of Making a Better Pill

Inside the Science of Making a Better Pill

Inside the Science of Making a Better Pill

Turning the active ingredients of a medicine into a tablet or liquid that is effective, safe and convenient is a crucial step in the development of a medicine, and the complexity of the process is often veiled behind the tidy final product we see. Having a medicine that is the right shape, taste,...

How Immuno-Oncology Taps Into the Body’s Own Immune System to Fight Cancer

How Immuno-Oncology Taps Into the Body’s Own Immune System to Fight Cancer

How Immuno-Oncology Taps Into the Body’s Own...

One of the most important advances in cancer therapies is a field known as immuno-oncology, which uses methods that tap into a patient’s own immune system to detect and destroy cancer cells. Experts predict that immuno-oncology will become one of the pillars of cancer treatment, alongside more...

When Bacteria Outsmart Antibiotics, Surveillance Can Help Battle Resistance

When Bacteria Outsmart Antibiotics, Surveillance Can Help Battle Resistance

When Bacteria Outsmart Antibiotics,...

Since bacteria grow and reproduce quickly, they also quickly adapt on a genetic level to pressures from the outside through genetic mutations and even through acquiring genes from other bacteria. If those genetic changes make the bacteria resistant to a given antibiotic, then it will survive when...

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