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Disruptive Science

Decoding Science: Cytokines

Decoding Science: Cytokines

Decoding Science: Cytokines

From the Greek “cyto” for cell and “kinos” for movement, cytokines orchestrate the immune system’s activity, and may be the key to understanding and treating autoimmune disorders.

Cryo-Electron Microscope Opens Resolution Revolution for Biological Imaging

Cryo-Electron Microscope Opens Resolution Revolution for Biological Imaging

Cryo-Electron Microscope Opens Resolution...

The cryo-electron microscope, or cryo-EM, is allowing scientists to image structures as small as viruses and ribosomes — the part of the cell where proteins are synthesized. More importantly, it does this without the need to turn the samples into crystals — the often tricky step needed when using...

When Diversity Means Better Medicine

When Diversity Means Better Medicine

When Diversity Means Better Medicine

By tapping into more diverse genomes, researchers are gaining novel insights into disease and drug safety. 

A New Frontier for AI: Helping Scientists Develop Potential New Medicines

A New Frontier for AI: Helping Scientists Develop Potential New Medicines

A New Frontier for AI: Helping Scientists...

Austin Huang, Associate Director and the Biomedical Data Science lead in Pfizer’s Genome Sciences and Technologies group, explains the role of artificial intelligence in drug development.

One of Mom’s Many Gifts to Her Baby: Maternal Vaccination

One of Mom’s Many Gifts to Her Baby: Maternal Vaccination

One of Mom’s Many Gifts to Her Baby: Maternal...

In recent years, maternal immunization has been steadily gaining acceptance as a means to pass infection-fighting antibodies to newborns. Current research shows that vaccines are safe for pregnant women. 

Fixing Broken Body Clocks

Fixing Broken Body Clocks

Fixing Broken Body Clocks

Every living being from fungi to frogs has an internal clock that normally runs on a 24-hour cycle.  In humans, this master clock resides in a tiny region of the brain’s hypothalamus and controls everything from hunger and sleep patterns to daily hormone fluctuations and body temperature.In...

Imagine a World Without Science

Imagine a World Without Science

Imagine a World Without Science

Evidence-based research makes many parts of our everyday lives possible. How would our lives be different without science?

 How Human 'Gene Knockouts' Are Pointing the Way to New Medicines

How Human 'Gene Knockouts' Are Pointing the Way to New Medicines

How Human 'Gene Knockouts' Are Pointing the...

Some people are naturally missing the working copy of a gene, the result of which can range from no effect at all to, occasionally, profound effects, such as very low cholesterol or congenital insensitivity to pain. Such significant, unusual medical characteristics are commonly referred to as ...

Consumer DNA Kits Give Research a Boost

Consumer DNA Kits Give Research a Boost

Consumer DNA Kits Give Research a Boost

Patients with lupus and inflammatory bowel disease (IBD) recently became a pivotal part of studies without ever stepping foot in a clinic or hospital, thanks to a collaboration formed between Pfizer and the genetic testing company 23andMe. The mission: find genetic clues that may someday lead to...

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