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Disruptive Science

New RNA Technology Could Get the Flu Vaccine Right, Every Year

New RNA Technology Could Get the Flu Vaccine Right, Every Year

New RNA Technology Could Get the Flu Vaccine...

We’ve been making the flu vaccine in nearly the same way for 70 years. A new technology based on RNA could disrupt that. ...

What is Green Chemistry?

What is Green Chemistry?

What is Green Chemistry?

The way contemporary chemists work is a lot different than the way their predecessors worked only a few generations ago. You might think that the change is due to new technologies or breakthroughs in scientific understanding, but that’s only partly right. One of the major reasons chemistry is...

Scientific ‘Swap Meet’: Pharma Competitors Form Novel Consortium to Share Materials

Scientific ‘Swap Meet’: Pharma Competitors Form Novel Consortium to Share Materials

Scientific ‘Swap Meet’: Pharma Competitors Form...

Just as an amazing meal often begins with the best ingredients, the most innovative compounds are likely to emerge when scientists have access to diverse and high-quality chemical building blocks. ...

Using ‘Omics to Understand the Rise in Breast Cancers Among Young Asians

Using ‘Omics to Understand the Rise in Breast Cancers Among Young Asians

Using ‘Omics to Understand the Rise in Breast...

Asian women, compared to their counterparts in western countries, are diagnosed with breast cancer at earlier ages and face a worse prognosis. ...

Helping the Liver Help Itself

Helping the Liver Help Itself

Helping the Liver Help Itself

Humans have practiced medicine for thousands of years, but the earliest results were decidedly mixed. Archaeological evidence reveals prehistoric physicians performed complicated tasks such as neurosurgery as far back as the Neolithic age. However, the evidence also suggests that prehistoric...

Unlocking the Secrets of a Protein “Superfamily

Unlocking the Secrets of a Protein “Superfamily"

Unlocking the Secrets of a Protein “Superfamily"

Large families can be complex. And while you may know some of its members individually, you can’t really gain a true understanding of their relationships and dynamics without considering the group in its totality. ...

Matching Drugs to Diseases: Advances in Targeting JAKs Leading to New Autoimmune Therapies

Matching Drugs to Diseases: Advances in Targeting JAKs Leading to New Autoimmune Therapies

Matching Drugs to Diseases: Advances in...

Janus kinases (JAKs) named after Janus, the Roman two-faced god of duality, are enzymes with two “faces,” or domains, that play a key role in signal transduction of cytokines, the molecular messengers that trigger the inflammatory and immune responses. Scientific discoveries related to JAKs...

Using DNA ‘Barcodes’ in the Search for New Drugs

Using DNA ‘Barcodes’ in the Search for New Drugs

Using DNA ‘Barcodes’ in the Search for New Drugs

Organic lettuce, endangered sharks, and now, new medicines. ...

Inside the Toxicology Lab: From Guardians of the Genome to Bottleneck Breakers and Beyond

Inside the Toxicology Lab: From Guardians of the Genome to Bottleneck Breakers and Beyond

Inside the Toxicology Lab: From Guardians of...

When it comes to creating new medicines, the stories that most often reach the public are the discoveries of new biological pathways or novel compounds. But in the nearly decade-long journey a medicine takes to get from the lab to patients, drug safety studies are an integral, though often behind...

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